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How the world got lost on
the road to an anti-aging pill
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February 11, 2021: by Bill Sardi
The focus of this report is resveratrol and its profound and unparalleled anti-COVID-19 properties. But before this report addresses resveratrol, some background information is needed.
There is not a corner of the world that has escaped awareness of a mutated corona cold virus of specious origin (man-made?) called COVID-19 that has rapidly has spread through human populations.
Though highly infectious and transmissible (almost everyone I know says they have experienced symptoms, even before a pandemic was called), COVID-19 is associated with 2.35 million accumulated deaths worldwide, or one death in 0.0003% (3 in 10,000) of the world’s population; with only 6% of these deaths (141,000) a result of COVID-19 alone, which amounts to 0.000018% (or 1.8 deaths per 100,000 people).
Compare that to 1.4 million people dying annually from tuberculosis, another lung infection, or 0.00018% (1.8 deaths per 10,000), or ten times that of COVID-19.
COVID-19’s symptomology inexplicably does not match up with any of the other seven known coronaviruses. It affects the nervous system, not just the respiratory tract. That means it can wreak havoc anywhere in the body.
Symptoms unique to COVID-19 include racing heart, kidney failure, digestive tract problems, loss of smell, memory impairment, numbness and tingling, eye twitching, profound weakness and fatigue, and apart from symptoms caused by other respiratory viruses (cough, fever, diarrhea).
These symptoms are difficult to distinguish from manifestations of lockdown and isolation, with so many people worldwide choosing to deal with this biological threat by drinking too much alcohol, using stimulants like coffee and tea and opting for sugary foods.
The fear created by public health authorities over COVID-19 appears to be misplaced and inappropriate, but once fear is instilled in a human population and exacerbated by a continued barrage of scary news reports, even contrary evidence is dismissed.
“What if?” is embedded in the back of people’s minds. “What if COVID-19 truthfully exists and it really is a virus no one in the world has immunity against?” People are dying horrific deaths in intensive care units around the world and we are told it is because of COVID-19.
So, the lesson here is to maintain health. Co-morbid conditions drastically increase mortal risk, diabetes in particular. Up to 80% of hospitalized elderly are malnourished and vulnerable to mortal outcomes when hospitalized for COVID-19. Most elderly hospitalized COVID-19 patients exhibit frailty.
COVID-19 may be strongly associated with respiratory deaths and acute organ failure but that doesn’t necessarily mean it causes hospitalizations or mortal outcomes.
As an historical example, a retrospective analysis of the 1918 Spanish flu found it was tuberculosis combined with a resultant staphylococcus bacterial infection that produced all the millions of deaths worldwide, not the H1N1 influenza virus which just may have been a bystander. Even Dr. Anthony Fauci, director of the National Institute of Infectious Diseases, said in 2008 that deaths attributed to the Spanish flu of 1918 were really caused by a staphylococcus bacterium, not influenza.
There are a number of essential nutrients, namely the trace minerals zinc and selenium and vitamins A, B1, C, D, that are required to maintain the human immune system and quell viruses (like COVID-19) and bacteria that invade the human body. These essential-for-life nutrients should be considered before opting to use resveratrol.
As a small molecule (molecular weight 228 Daltons), resveratrol can pass through cell walls and enter/influence the genetic machinery within the nucleus of living cells.
Resveratrol (rez-vair-ah-trol), a unique small molecule in nature that serves as an anti-fungal agent in plants, berries and grapes, is extracted from Giant Knotweed to yield a potent herbal extract and has been called out by infectious disease specialists for its broad anti-COVID-19 properties.
Its broad biological activity and number of genes it controls is exceptional, being called “a miraculous natural compound for diseases treatment” in the journal of Food Science & Nutrition. When combined with other natural molecules such as found naturally in fermented grapes (wine) it can exert a 9-fold greater control over genes known to produce longevity.
Given that resveratrol molecularly mimics a calorie restricted diet, it is perceived by the human body to send the same signals as starvation. This food deprivation signal then activates a master survival gene – Sirtuin1.
Resveratrol puts the body on alert. It triggers a molecular switch known as Nrf2 that activates all the cells in the body to produce their own internal enzymatic antioxidants – catalase, superoxide dismutase (SOD) and glutathione.
By virtue of its ability to activate this endogenous antioxidant system, it pre-protects the brain and heart from potential damage caused by the lack of oxygen such as occurs during a stroke or heart attack. Resveratrol even is beneficial in restoring brain and heart pumping function after a stroke or heart attack.
Resveratrol also inhibits blood clotting, a major factor in all diseases.
DNA is comprised of genes (bundles of DNA) that are presented on a double helix (a coiled ladder). If the DNA strand is damaged and detached at one end it is called a SINGLE-STRAND DNA break. If broken at both ends, a DOUBLE-STRAND DNA BREAK (mutation).
In the following diagram the amino acid TYROSINE is seen in the water cytoplasm of cells. An enzyme TYROSINE SYNTHETASE is then produced which is then relocated via RESVERATROL into the genetic center of cells, the NUCLEUS.
Once relocated it activates a DNA repair gene called PARP-1 to facilitate the mending of broken genes (single or double strand DNA repair). Scientists at the Scripps Institute call this a “miracle.” If you want to read the scientific study about this, published in NATURE in 2015), you can link to it here.
A remarkable feature of resveratrol is that it accomplishes this DNA repair in very low doses, about a thousand-times lower than demonstrated in other studies. A couple of glasses of dark aged red wine (providing ~1 mg resveratrol per 5-ounce glass) would do!
This runs counter to many news reports which dismiss resveratrol as an anti-aging agent because one would need to drink over a thousand bottles of wine per day to obtain the amount of resveratrol provided in a 500 milligram pill.
By the way, resveratrol also delays the S-phase of the cell renewal cycle in order to facilitate DNA repair. (Sorry for the scientific lingo.) Resveratrol renews cellular organelles called mitochondria that generate cell energy in the same manner it repairs DNA via tyrosine (as explained above). When cells in the body can no longer renew themselves (make daughter cells), they become senescent which results in fragility of older adults. Resveratrol reverses cell senescence, but simultaneously induces senescence in cancer cells that leads to their early demise.
Resveratrol exhibits broad biological activity against all known viruses (influenza, Epstein-Barr, herpes, HIV, enterovirus, MERS and SARS coronaviruses, etc.), and COVID-19 in particular.
Resveratrol addresses the seven known mechanisms associated with COVID-19: 1) regulation of the immune system; 2) viral entrance to the cell; 3) viral replication; 4) inflammation; 5) oxidation; 6) blood clotting and 7) blood vessel constriction.
Here is a comprehensive list of the anti-COVID-19 properties of resveratrol:
The COVID-19 coronavirus is an RNA virus. The MODERNA COVID-19 vaccine is an RNA vaccine. Gene activation involves transcription of DNA into messenger RNA and then to gene-derived proteins.
Merle Nass MD, calls attention to the fact messenger RNA (or any RNA) can potentially be converted to DNA in the presence of the enzyme reverse transcriptase. That DNA could then become linked to your native DNA. There is the possibility of vaccine-RNA being converted to DNA and then permanently inserted into our DNA. (Resveratrol, a red wine molecule, by virtue of its ability to inhibit reverse transcriptase, could put a halt to this potential biogenetic hazard.)
Over a decade after being summarily dismissed by the medical research community and almost totally shunned and ignored by clinical medicine, research studies continue to extol the health and longevity properties of resveratrol. In this era of over-vaccination, resveratrol may serve as a rescue remedy for those who fail immunization.
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