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How the world got lost on
the road to an anti-aging pill
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May 8, 2019: by Bill Sardi
Stents (wire props) are placed within narrowed (stenotic) or blocked (blood clotted) coronary arteries that feed the heart with oxygenated blood over 2 million times a year in the U.S., mostly among men and women with angina chest pain.
The use of a coronary artery stent may sometimes be worse than the patient’s disease. The history of coronary artery stenting is one of presumed effectiveness. Stent-induced heart attacks and deaths have plagued this widely practiced intervention since its inception.
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March 28, 2019: by Bill Sardi
Sweat, Fast, Donate Blood, Limit Red Meat, Supplement With Iron/Copper Chelators (Fisetin, Quercetin, Resveratrol, IP6 Rice Bran, Nucleotides) To Reduce The Population Of Senescent Cells In Your Body & Live Longer & Healthier Than You Ever Imagined
To Stay Young… Kill “Zombie” Cells — Scientific American
Now you and your loved ones can play the game of life into extra innings and they aren’t going to have to send in a pinch runner for you, and you won’t be forced to retire and you can still hit home runs!
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March 6, 2019: by Bill Sardi
Longevity seekers may not have sufficient information to give them an understanding of what lies ahead as they enter their eighth and ninth decades of life. The problem is not cataracts, erosion of bone (osteoporosis), loss of muscle mass, heart failure or mental decline per se, that are inevitable consequences of living long. These are individual features of aging that emanate from a problem called cell senescence.
During the years of youth cells divide (mitosis), die off (called apoptosis) and renew themselves (daughter cells). But with advancing age a significant portion (5% to 20%) of cells don’t divide and renew.
Recently it has been discovered that these zombie senescent cells drive aging and increase frailty and mortality. Some 25-50% of people over the age of 85 today are frail. Frailty is 15% in the elderly population and 54% among those hospitalized. When senescent cells were injected into young mice, they become old and frail, and they also died prematurely. This is newly recognized science.
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February 13, 2019: by Bill Sardi
By chance a research group at Cornell University discovered that white blood cells known as neutrophils stick to the smallest blood vessels in the human body (called capillaries) and reduce blood flow to the brain. Unblocking these capillaries with a monoclonal antibody (antibody blockers) that prevent the adhesion of roaming neutrophils to capillary walls improves blood flow in the brain. An immediate restoration of mental performance and working memory of laboratory animals was observed.
The discovery has profound application among adults who face age-related memory decline. The ground-breaking report was published in the journal Nature Neuroscience.
Read the whole post »
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January 10, 2019: by Bill Sardi
Nothing like putting a damper on the plans of billionaire oligarchs who have cooked up an expensive cure for human aging that very few but themselves can afford. It’s the transfer of blood plasma from a young donor to an old recipient to produce an anti-aging effect. The idea was fostered by recently published studies that show the conjoining of blood circulation of a young animal with an old one results in the old animal becoming younger biologically.
That experimental procedure is called parabiosis. Of course, old humans aren’t stitching their arteries together with younger people as they did in the animal lab but rather receive infusions of blood plasma from young donors. [Nature 2015]
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January 4, 2019: by Bill Sardi
The title of unluckiest and unhappiest man in the world was assigned to Mr. Tsutomu Yamaguchi who during WWII was A-bombed at Hiroshima, Japan and then was evacuated to Nagasaki where he survived a second A-bomb attack. The A-bombs did not shorten his life. He lived 93 years. Another survivor, Sunao Tsuboi, at the age of 20 was 1.2 kilometers from the A-bomb epicenter in Hiroshima. He is alive and healthy today at age 93 (2018).
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January 2, 2019: by Bill Sardi
Main points:
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December 26, 2018: by Bill Sardi
Photo: Corey Kilgannon
Before I get to the incredible story of Anthony Mancinelli, age 107, there is also the story of Joao Coelho de Souza, born March 10, 1884 (there isn’t supposed to be anybody alive that was born in the 1800s) who has records to prove he was 131 years old in 2016. Is the Coelho de Souza report valid?
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December 13, 2018: by Bill Sardi
CLINICIAN’S GUIDE TO RESVERATROL DISPELS INACCURACIES AND MYTHS ABOUT RESVERATROL
FOR HEALTH PROFESSIONALS
This report pertains to:
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December 10, 2018: by Bill Sardi
In the anti-aging pill arena 2018 has been the year of senolytic drugs – the prospect that synthetic molecules could soon erase the ravages of aging produced by a progressive aging process called cell senescence.
Four major milestones have been achieved in rapid fashion.These four developments started in 2011 with an animal study where the destruction of “senescent” cells improved the lifespan and health span of laboratory mice.That was followed by (2) the identification of small natural molecules that are capable of clearing the body of “senescent” cells; then (3) these molecules were then shown to improve the lifespan and function of aged mice; and (4) pre-clinical studies show these molecules are successful in quelling a wide range of maladies.
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