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June 19, 2012: by ResveratrolNews
June 19th, 2012 in Health
A natural compound found in some fruits, nuts and red wine may enhance exercise training and performance, demonstrates newly published medical research from the University of Alberta.
Principal investigator Jason Dyck and his team found out in experiments that high doses of the natural compound resveratrol improved physical performance, heart function and muscle strength in lab models.
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June 12, 2012: by Bill Sardi
We hear of potential problems associated with exposure to herbicides and pesticides, artificial sweeteners, drugs in tap water, heavy metals, plasticizers, petroleum products, bisphenol A hormone disruptor in the lining of tin cans, as well as chlorine, fluoride, and hundreds of other chemicals. Maybe some human exposure to trivial doses of potential toxins is harmless and is rapidly negated or excreted by detoxification systems within the human body, but what about all of them representing a total modern chemical/environmental threat? A study of these aggregate toxins may be beyond what modern toxicology can examine.
Researchers Melissa L Sokolosky and Michael J Wargovich at the Hollings Cancer Center, Medical University of South Carolina, explore reasons why there are certain less developed geographical regions in the world that exhibit a 26-fold lower incidence for colon/rectal cancer compared to areas where more advanced human civilizations live. This fact suggests something having to do with modern living is involved in the promotion of cancer.
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June 10, 2012: by Bill Sardi
Say it again: nicotinamide riboside (nik-oh-tin-amide ry-bo-side).
In the wake of the many advances and setbacks involved in marketing resveratrol pills, another small vitamin-like molecule enters the anti-aging pill market, that is, if it can be produced economically and be shown to work in humans at a much lower dose than in the animal lab.
The “new molecule” is a cousin of niacin. Said to be an incredibly small molecule that is difficult to find in foods (it is found in the whey of milk and beer), its molecular weight is 255.247 Daltons, slightly larger than the red wine molecule resveratrol. It works on some of the same gene targets as resveratrol, such as SIrtuin1 and Sirtuin 3, and subsequently FOXO1, Pgc1a and SOD, genes known to produce anti-aging effects.
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May 29, 2012: by Bill Sardi
Yes, what is obvious has been confirmed. Despite unfounded claims that all of the research studies showing resveratrol protects heart muscle tissue during a heart attack, even Wikipedia spreads misinformation that that fact is in question due to bogus allegations of scientific fraud against a leading resveratrol scientist. Canadian researchers unequivocally show that resveratrol protects the heart under conditions of biological stress induced by instillation of hydrogen peroxide by maintaining antioxidant enzymes (catalase, superoxide dismutase). Once damaged (scarred), heart muscle cells (cardiomyocytes) are not rapidly repaired. So it is critical to protect these cells. Resveratrol does something that no existing cardiac drug an do — protect the heart prior to a heart attack (this is called cardioprotection). It has been called the most ideal form of heart protection. Based upon animal lab studies, cardioprotection has been demonstrated to have the potential to turn otherwise mortal heart attacks into non-mortal events, which is more than aspirin or statin drugs can do. — Bill Sardi, ResveratrolNews.com
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May 16, 2012: by Bill Sardi
The fact is, such a pill already exists.
Click on the underlined links above to learn more.
–Bill Sardi, ResveratrolNews.com
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May 9, 2012: by ResveratrolNews
From: The Association for Research in Vision & Ophthalmology (ARVO) annual meeting, Fort Lauderdale, Fla.,
Ft. Lauderdale, FL (May 6, 2012) – There may be new found hope for patients whose vision is threatened when medicine injected directly into the eyes fails to cause abnormal blood vessels to recede. While injectable drugs called angiogenesis (an-gee-oh-jen-esis) inhibitors are considered a modern miracle and have become the standard of care for patients with the fast-progressive form of macular degeneration, they are not foolproof. For the first time researchers report that an oral nutriceutical, used on a last-resort clinical basis, rapidly restores vision to otherwise hopeless patients who face permanent loss.
Stuart Richer OD, PhD, Director, Ocular Preventative Medicine-Eye Clinic, James A. Lovell Federal Health Care Center, North Chicago, Illinois, says all other therapies were exhausted before employing the oral nutriceutical under compassionate-use protocols on a case-by-case basis. Usually most patients respond to medicine injected directly into the eyes, he says, but only about one in three patients recover driving vision and one in six patients go on to experience permanent vision loss and others may refuse needle injections directly into the eyes, making them candidates for this rescue medicine.
Three successfully treated cases were presented at the annual Association for Research in Vision & Ophthalmology meeting in Ft. Lauderdale, Florida.
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May 2, 2012: by Bill Sardi
http://www.nrcresearchpress.com/doi/pdf/10.1139/y2012-065
Dr. Thomas Netticadan
Canadian Centre for Agri-food Research
in Health and Medicine,
Winnipeg, Manitoba
Thank you for your comments published at Canadian Journal Physiology & Pharmacology regarding resveratrol research. ( http://www.nrcresearchpress.com/doi/pdf/10.1139/y2012-065 )
Let it be said that:
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April 21, 2012: by ResveratrolNews
Abridged summary: researchers have found that even very low dose intermittent exposure (twice in a 5-day period) to hydrogen peroxide, which is generated by exposure to unfiltered sunlight, induces aging of cells in the outer layer of the skin (epidermis) but that the red wine molecule resveratrol completely blocks senescence of these cells which may be chronically exposed to solar ultraviolet radiation.
Researchers in the experiment presented below show that hydrogen peroxide (H2O2-)induced premature senescence in primary human keratinocytes (cells found in the outer layer of the skin/epidermis) can be prevented by AMPK activation. (AMPK is a master metabolic activating enzyme.)
Cells that are senescent are no longer capable of dividing and skin renewal. Thus, researchers found that: (1) a low dose of hydrogen peroxide (H2O2 50 µM) activates two primary genes (p53 and secondarily p21)in these cells and subsequently increased SA-Galactosidase (SA-Ga1) activity, a marker of cellular senescence, and that (2) prior activation of AMPK by resveratrol prevented these H2O2-induced changes
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April 17, 2012: by Bill Sardi
According to a recent survey, 1 in 10 drugs were prescribed for off-label (unproven) uses, most which were not substantiated by existing science. (Archives Internal Medicine April 16, 2012). Physicians frequently respond to patient inquiries about dietary supplements by saying they are “unproven.” However, that doesn’t seem to bother physicians if it is a drug.
Furthermore, there is no drug that cures cancer (chemotherapy drugs only need to temporarily shrink a tumor by 50% before drug/tumor resistance sets in to gain FDA approval).
There is no single drug (diuretics, beta blockers, ACE inhibitors, calcium blockers) that adequately controls high blood pressure, and then none address the most common cause of hypertension (inability of blood vessels to dilate upon mental or physical exertion).
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April 12, 2012: by Bill Sardi
Noted herbal researcher Bahrat Aggarwal PhD, of the University of Texas MD Anderson Cancer Center in Houston is the second major herbal researcher to be accused of scientific fraud this year. Word that 65 of his published papers were under scientific review began to be leaked first on the internet before news reports confirmed an investigation is underway.
Like Dipak Das, PhD, the University of Connecticut researcher who was charged with over a hundred counts of scientific deceit in January of this year, both researchers stand accused of altering graphic images in their published papers. And in both instances, there is unequivocal evidence of altered images in these published papers. However, interpretation of whether these altered images represent honest mistakes or intentional trickery is a bit more difficult.
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