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March 8, 2012: by Bill Sardi
(March 8, 2012)- Millions of Americans are paying with their lives and their eyesight for the US Food & Drug Administration’s denial that nutriceuticals prevent, treat or cure disease says Bill Sardi, dietary supplement industry executive and health writer, speaking at the annual Nutracon meeting in Anaheim, CA this week.
“Nutriceuticals, a more sophisticated name for dietary supplements, do in fact prevent, treat and cure essential nutrient deficiency diseases such as vitamin D for rickets, vitamin C for scurvy, vitamin B1 for beri beri, as well as many chronic diseases, yet the FDA bans (censors) statements of fact, keeping the public in the dark over the obvious health benefits and cost effectiveness of nutriceuticals,” says Sardi.
“The US FDA maintains a narrow pharmaceutical model for chronic diseases, which are basically treated as drug deficiencies. The FDA maintains dietary supplements must become expensive drugs before statements can be made they cure or treat disease, which is absurd,” says Sardi.
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February 16, 2012: by Bill Sardi
Exclusive at www.resveratrolnews.com
Jennifer Aniston, arguably judged the most attractive female on the planet at the moment, has risen to this “most admirable” spot at age 43. Menshealth.com goes a step further, anointing Aniston as the hottest woman of all time.
According to an article in the Sydney Morning Herald, Aniston says she maintains her shape and beauty by daily exercise, pumping small hand weights in hotel rooms, and taking dietary supplements such as fish oil and resveratrol (rez-vair-ah-troll), the red wine molecule. No wonder she gets admired by a male health mag, her pill regimen beats that of most celebs who have been known to pop stimulants of all kinds. No, Aniston is not likely to enter rehab anytime soon to go through withdrawal from resveratrol pills. Is the fairer sex missing some beauty secret here? Maybe.
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February 10, 2012: by Bill Sardi
Over eight years after a Harvard University researcher mistakenly identified the primary gene target of resveratrol (rez-vair-ah-troll) as a survival gene (Sirtuin1) that is also variably activated by calorie restricted diets, National Institutes of Health (NIH) researchers say they have now identified an enzyme (phosphodiesterase4 or PDE4) as the first gene target of resveratrol. Specifically, this enzyme is inhibited by resveratrol, known as a red wine molecule. All of the antioxidant molecules in red wine are enzyme inhibitors.
The Sirtuin1 gene is not totally out of the picture, it is activated indirectly in the gene pathway along with other important metabolic gene targets such as NAD, PGC1a and AMPK. The study, which was conducted in mice, needs to be replicated in humans.
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February 5, 2012: by Bill Sardi
Unless you are a died-in-the-wool resveratrol pill user, you are likely having doubts over whether you should continue taking these so-called red wine pills now that the science published by a leading researcher in the field has been called into question (more about that below). Strangely enough, the science behind resveratrol’s miraculous ability to protect the human heart is very well founded, but when did solid science ever influence consumers anyway?
The record shows consumers of resveratrol pills are more likely to fall for a phony sales pitch rather than phony science. Except for a brief period in 2009 when online spammers falsely claimed their products were endorsed by Oprah Winfrey, pandered resveratrol pills as a cure-all for whatever ails mankind, made free bottle offers that came with fine print and unwanted monthly $85 credit card billings for more resveratrol pills and sold millions of bottles of these pills, consumers of dietary supplements have not widely adopted resveratrol pills into their daily pill regimens and appear to be paying a steep price for it with their lives.
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February 4, 2012: by admin
It’s Not Sirtuin1, it’s cAMP-dependent phosphodiesterases
While researchers have argued over whether Sirtuin1 is the direct or indirectly-activated gene responsible for its molecular mimicry of calorie restriction, researchers now claim resveratrol works directly by inhibiting enzymes called cAMP-dependent phosphodiesterases which then triggers a cascade of events that includes Sirtuin1. You also see the name of a pharmaceutical company in Japan participating here. (see attached paper)
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January 30, 2012: by admin
In recent days allegations of scientific fraud by a leading researcher who has conducted experiments using resveratrol, a red wine molecule, have been aired. Negative news report have cast a pall over the idea of drinking red wine or red wine pills as an elixir for what ails the heart. Was the science behind red wine pills all made up, as one popular radio commentator recently said? Preventive cardiologist Nate E. Lebowitz, M.D., FACC, with the Advanced Cardiology Institute in Ft. Lee, New Jersey, answers questions on this topic:
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January 20, 2012: by admin
As one can learn from the following 2006 report in NATURE METHODS, western blot tests are a perfect tool to out any vulnerable scientist.
According to the following report, 25% of accepted manuscripts contained at least one “inappropriately manipulated figure,” but obviously the authors of these papers did not all face expulsion from their institutions as did Dr. Das. This report in Nature Methods does not say that editors also reject papers where western blot images that are not of sufficient quality to be reproduced, forcing authors to enhanced the images. But it should. Furthermore, apparently most of these cases involve researchers who did not have intent to deceive.
The question arises, why didn’t the editors of the 11 journals involving 26 papers submitted by Dr. Das ever catch these “altered images” in their peer review and scientific integrity efforts? It seems to me researchers should submit raw images and let the journals take all the ethical criticism rather than risk their careers over this. Would firing 25% of the researchers fix the problem? Obviously no. But it’s OK to pillory Dr. Das.
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January 16, 2012: by Bill Sardi
In recent days a clear message has been sent to laboratory investigators – cooperate with a resveratrol pill maker and your career will be over. And this is not the first time this has happened.
If you were listening to Rush Limbaugh on the radio in the past week you heard him impugn the work of East-Indian born researcher, Dipak Das PhD., a University of Connecticut researcher widely known for his work in studying resveratrol (rez-vair-ah-troll), a red wine molecule, for heart health.
According to Limbaugh and over 300 news agencies, Dr. Das is unequivocally guilty of doctoring tests that measure the amount of proteins in tissues, a test called a western blot. The University of Connecticut, Dr. Das’ employer, released a damning report that appears to present undeniable evidence that Dr. Das had doctored images on his office computer and published those images in a scientific journal in 2008.
But hold on. The alleged faulty tests in no way altered the outcome of his research studies. The western blot test was only one of many tests used to draw scientific conclusions in published studies. Furthermore, other independent labs, including the National Institutes of Health (NIH) itself, validated Dr. Das’ work, as did researchers in Europe and Japan.
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January 12, 2012: by ResveratrolNews
January 12, 2012: An East Indian researcher accused of scientific misconduct by a University of Connecticut Health Center review board claims all of the allegations against him can be “easily refuted” and that the charges against him involve prejudice within the university against Indian researchers. Six other East Indian researchers were also named as “potential respondents” to charges of scientific fraud, but no researchers of other ethnicities.
Scott Tips, a California-based attorney representing the accused, Dr. Dipak Das, calls into question the following irregularities in the University’s 600-page report which claims Dr. Das doctored images of tests conducted at his laboratory or instructed others to doctor them. Some of these irregularities include:
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December 18, 2011: by Bill Sardi
Available in a PDF version as well – download here
“May the force be with you.” – Star Wars
Strange as it may seem, largely because of difficulties in figuring out how to commercialize on what it promises, both alternative and conventional medicine fail to put into practice a compelling discovery that promotes health and longevity in an unmatched fashion.
It’s not a high-tech invention. It is not a patentable process. It is not a machine or a drug. Nor is it new. It has been recognized in the medical literature for decades now.
It is an adaptive internal response to mild biological threats that trigger incomparable defenses in the human body.
Despite considerable personal investigation into this topic, even the most avid health nut or PhD pursuer of longevity is likely to have missed the greatest mechanism to promote the human healthspan and lifespan ever discovered because it is not found in our external world but is rather a built-in adaptive response within the human body that has many triggers.
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